Experience With 500 Simultaneous Pancreas-Kidney Transplants

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First Canadian experience with donation after cardiac death simultaneous pancreas and kidney transplants.

BACKGROUND Compared with neurologic determination of death (NDD) donor organs, donation after cardiac death (DCD) donor organs have traditionally been considered of inferior quality owing to warm ischemia experienced during procurement. We present, to our knowledge, the first analysis of simultaneous pancreas and kidney (SPK) transplants using DCD donor organs in Canada. METHODS We carried ou...

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Donor Characteristics in 1,000 Consecutive Simultaneous Pancreas-Kidney Transplants

In 2003, Krieger et al. from our group published a manuscript which investigated the use of pancreas grafts for transplantation in different UNOS regions in the United States (1). It was reported that the utilization of pancreata showed a wide variation depending on the region. To approach some degree of standardization, we calculated the ratio of pancreata used for transplantation with the num...

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One thousand simultaneous pancreas-kidney transplants at a single center with 22-year follow-up.

OBJECTIVE Simultaneous pancreas-kidney transplantation (SPK) is a procedure which frees the diabetic patient with end-stage nephropathy from dialysis and daily insulin injections. The purpose of this study is to report long-term outcomes of this procedure, and describe surgical and medical complications. METHODS The analysis includes 1000 consecutive SPKs performed between 1985 and 2007. Blad...

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Risk Factors for Type 1 Diabetes Recurrence in Immunosuppressed Recipients of Simultaneous Pancreas–Kidney Transplants

Patients with type 1 diabetes (T1D) who are recipients of pancreas transplants are believed to rarely develop T1D recurrence in the allograft if effectively immunosuppressed. We evaluated a cohort of 223 recipients of simultaneous pancreas-kidney allografts for T1D recurrence and its risk factors. With long-term follow-up, recurrence was observed in approximately 7% of patients. Comparing the t...

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Outcome in Pancreas Grafts After BK Virus Viremia in Simultaneous Pancreas-Kidney Transplants: A Single-Center Case Report

A of immunosuppression (IS) is clearly the infections that jeopardize graft and patient survival. Reactivation of BK virus and histologically proven BK virus nephropathy (BKVN) after kidney transplantation (KT) are well described, resulting in renal graft loss in up to 15% of such patients. Described risk factors are lymphocyte-depleting agents, tacrolimus (Tac)–based IS, diabetes mellitus, and...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1998

ISSN: 0003-4932

DOI: 10.1097/00000658-199809000-00002